Transplantation represents a life-changing therapeutic option for select patients with diabetes, particularly those with end-stage renal disease (ESRD). These flashcards are designed to help pharmacists and healthcare professionals quickly recall the 2018 Clinical Practice Guidelines regarding the specific benefits of kidney, pancreas, and islet transplantation, as well as the management of post-transplant complications.
Key Topics Covered:
Kidney Transplantation: Understanding the evidence that kidney transplantation provides superior long-term survival compared to dialysis for patients with diabetes and ESRD.
Simultaneous Pancreas-Kidney (SPK): Identifying SPK as a strategy to prolong insulin independence and improve kidney graft survival in Type 1 diabetes.
Islet Transplantation: Recognizing the role of islet allotransplantation in preventing severe hypoglycemia, despite the trade-off of long-term immunosuppression.
Islet Autotransplantation: Recalling the indication for this procedure in patients undergoing total pancreatectomy for benign disease to prevent labile diabetes.
Post-Transplant Diabetes (PTDM): Managing the risks associated with PTDM, including its impact on graft loss, cardiovascular disease, and mortality.