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CDE Diabetes

Flashcards: Sexual Dysfunction and Hypogonadism in Men with Diabetes (Chapter 33)

Erectile dysfunction (ED) affects a staggering 35% to 90% of men with diabetes and often serves as a “canary in the coal mine” for silent coronary artery disease. These flashcards are designed to help pharmacists and healthcare professionals quickly recall the 2018 Clinical Practice Guidelines regarding screening protocols, the cardiovascular implications of ED, and the safe management of hypogonadism.

Key Topics Covered:

  • Vascular Warning Signs: Understanding the evidence that ED may precede the onset of coronary artery disease, serving as a critical marker for vascular health.

  • Screening Protocols: Memorizing the recommendation to screen all men with diabetes for ED using a sexual function history or the IIEF-5 questionnaire.

  • First-Line Therapy: Identifying PDE5 inhibitors as the first-line treatment and recalling the absolute contraindication for their use with nitrates.

  • Hypogonadism Diagnosis: Recalling the specific requirement for morning total testosterone measurement to accurately diagnose biochemical hypogonadism.

  • Testosterone Replacement: Understanding the indications for replacement therapy—specifically for symptomatic men with confirmed low testosterone—and its potential to improve insulin sensitivity.