How Well do You Know DOACs? – Interactive Quiz

DOAC Therapy

With guidelines recommending the use of DOACs for stroke prevention in atrial fibrillation (AF), we have seen an increasing number of patients using these therapies.  There are common errors that are made in terms of dosing, monitoring and managing patients on these therapy.  Thrombosis Canada has some incredible tools on appropriate use of DOACs and clinical tools for practice.  A couple of great tools include the following:

If you haven’t reviewed the Thrombosis Canada website, I would encourage you to do so.

DOACs Interactive Quiz (15 T/F Questions)

I thought I would do a quiz on some of the key therapeutic issues with DOACs.  I hope you like it.

1. Antacids can decrease the absorption of all DOACs

2. St. John's Wort can decrease the efficacy of apixaban

3. Patients using a DOAC can continue taking their medication if having a cleaning or uncomplicated tooth extraction

4. When switching from warfarin to DOAC, they should start the DOAC and stop warfarin on the same day

5. The dose of apixaban for stroke prevention in AF is 5 mg BID

6. Dabigatran can be crushed or chewed, but the capsules can be opened and mixed in apple sauce in patients who can't swallow tablets.

7. The standard dose of rivaroxaban for stroke prevention in AF is 20 mg once daily

8. Edoxaban can be placed in a dosette or patient packaging.

9. There are several food interactions with several of the DOACs.

10. Apixaban is ideally taken with food.

11. Rivaroxaban is the only DOAC with once daily dosing for stroke prevention in AF.

12. DOACs are known to interact with alcohol

13. Patients on DOAC therapy do not need routine blood testing

14. Apixaban has been shown to be more effective than dabigatran in head-to-head trials

15. Rivaroxaban must be taken with food.



  1. NOACs/DOACs*: Comparison And Frequently Asked Questions
  2. Direct Oral Anticoagulation (DOAC) Monitoring Checklist for Pharmacists
  3. NOACs/DOACs*: Perioperative Management