I present quite often on travel medicine and often get questions regarding the prevention and treatment of common travel-related conditions. I thought I would provide some background on travellers’ diarrhea as it is the most is the most predictable travel-related illness and occurs in a large number of travellers to resort destination .1
Travellers’ Diarrhea
The incidence rates of travellers’ diarrhea (TD) range from 20% to 90% for travel to low and middle-income countries (e.g. much of the Caribbean and Mexico).2 Attack rates range from 30% to 70% of travellers, depending on the destination and season of travel.1
Key Facts About Travellers’ Diarrhea
- Mainly caused by the ingestion of contaminated food and beverages
- Bacterial pathogens are responsible for most infections.
- Bacteria account for 80-90% of TD1 with enterogenic Escherichia coli (ETEC) accounting for 1/3 of the cases from the Caribbean and Latin America2
- Viral and protozoal infections account for the remaining 10-20% of TD cases1
- Untreated bacterial TD usually lasts 3–7 days. Viral TD generally lasts 2–3 days.1
- The risk of TD varies based on the region of travel. The world can be divided into three different TD risk categories:1
- Low-risk countries include the United States, Canada, Australia, New Zealand, Japan, and countries in Northern and Western Europe
- Intermediate-risk countries include those in Eastern Europe, South Africa, and some Caribbean islands
- High-risk areas include most of Asia, the Middle East, Africa, Mexico, and Central and South America
- Most travellers with TD will completely recover within a few days. Approximately 3% to 17% of patients with TD will develop post-infectious irritable bowel syndrome (PI-IBS).3
Did you know?One bout of TD does not prevent future attacks. It is common to have >1 episode of TD during a single trip.1 |
Clinical Presentation
- Travellers’ diarrhea symptoms not only include the passage of loose stools but commonly include:2
- Nausea
- Vomiting
- Abdominal cramps or pain
- Fever
- Blood in stools (dysentery)
Changes in Classification of Travellers’ Diarrhea
In the past, severity of TD was determined by the number of bowel movements in a day. The 2017 International Society of Travel Medicine (ISTM) Guidelines for the prevention and treatment of travelers’ diarrhea: a graded expert panel report, recommended a change in classification from the number of bowel movements to the level of impairment caused by the TD.4 This classification was recommended as some patients with infrequent bowel movements (1-2 stools) with severe cramps and fever may be significantly more distressed than more frequent bowel movements without cramps or pain.4
ISTM Classification of Travellers’ Diarrhea4 | |
Mild (acute) | Diarrhea that is tolerable, is not distressing, and does not interfere with planned activities |
Moderate (acute) | Diarrhea that is distressing or interferes with planned activities |
Severe | Diarrhea that is incapacitating or completely prevents planned activities; all dysentery (passage of grossly bloody stools) is considered severe
NOTE: if there is significant blood in the stools, the traveller should seek medical care |
Food and Beverage Recommendations for Travellers
The Travel Medicine: Expert Consult is a great reference for all healthcare professionals interested in travel medicine. In the travellers’ diarrhea chapter they have some excellent food and beverage recommendations.
Food, Beverage and Setting Recommendations for Travellers5 | |||
Category | Safest choice | Probably safe | Unsafe |
Food | Hot, thoroughly grilled, boiled
Processed and packaged Cooked vegetables and peeled fruits |
Dry items
Hyperosmolar items (jams, syrup) Washed vegetables and fruits (if washed in potable water) |
Salads
Sauces and salsas Uncooked seafood Raw or poorly cooked meats Unpeeled fruits Fruit without a thick peel like berries Unpasteurized dairy products Cold desserts |
Beverages | Carbonated soft drinks
Carbonated water Boiled water Purified water (iodine or chlorine |
Fresh citrus juices
Bottled water Packaged ice (machine made) |
Tap water
Chipped ice Unpasteurized milk |
Setting | Recommended restaurants | Local home | Street vendors |
Prevention and Treatment with Pharmacotherapy
I will cover the role of antibiotics, Dukoral®, bismuth subsalicylate, loperamide and probiotics in the prevention and prevention of TD in a future post.
References
- Connor B. Travelers’ Diarrhea – Chapter 2 – 2018 Yellow Book | Travelers’ Health | CDC. https://wwwnc.cdc.gov/travel/yellowbook/2018/the-pre-travel-consultation/travelers-diarrhea. Accessed June 26, 2017.
- Public Health Agency of Canada Government of Canada. Statement on Travellers Diarrhea. http://www.phac-aspc.gc.ca/tmp-pmv/catmat-ccmtmv/diarrhea-diarrhee-eng.php. Published April 31, 2015. Accessed December 10, 2017.
- Steffen R, Hill DR, DuPont HL. Traveler’s Diarrhea: A Clinical Review. JAMA. 2015;313(1):71. doi:10.1001/jama.2014.17006.
- Riddle MS, Connor BA, Beeching NJ, et al. Guidelines for the prevention and treatment of travelers’ diarrhea: a graded expert panel report. J Travel Med. 2017;24(suppl_1):S63-S80. doi:10.1093/jtm/tax026.
- Ericsson CD. Chapter 17 – Prevention of Travelers’ Diarrhea. In: Keystone JS, Kozarsky PE, Freedman DO, Nothdurft HD, Connor BA, eds. Travel Medicine (Second Edition). Edinburgh: Mosby; 2008:191-196.